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Medicine still doesn’t have successful cure for many viral illnesses. In the struggle against viruses, best results were attained by the use of prophylactic procedures, first of all the vaccination.
Good experiences with propolis in most frequent viral illnesses (cold, flu) contributed to testing of it’s influence on different viruses. Research undoubtedly indicates that propolis has indirect and direct effect - direct antiviral effect and indirectly it’s stimulating specific immunological defenses.

The indirect antiviral effect is based on the activity in viruses DNA. In some sorts (Herpes simplex, influenza, Herpes genitalis, Herpes zoster, Variola vera major, reo-virus etc.) it prevents its replication (in other words the multiplication inside the cell) and it also reduces the DNA synthesis that manifests itself in decrease of viral activity (1,2,3,4). In some oncogene viruses its interrupting transformation of the healthy cells to carcinogenic cells by means of decomposing their DNA (the fragmentation) and at the same time moves the mechanism of apoptosis with reference to death of transformed station (5,6,7). Research at the “Ruder Boskovic” Institute in Zagreb confirms that native propolis also kills tumor cells and deformed cells (apoptosis), but it doesn’t effect healthy cells.

The base of indirect effect is specific strengthening of the immunological system, which is obvious in increased number of lymphocytes and antibodies as an answer to viral infections (8). It is interesting that the vaccine (weakened viruses) in combination with propolis is more efficient in raising the immunological defense than the vaccine itself (9).

Clinical research showed faster process of recovery in genital herpes in men and women by local use of greases with propolis substances than with the medicine acyclovir (10). In case of cold virus taking of propolis is accelerating the time of recovery by 2.5 times (11).

Research is unequivocally indicating that propolis, as the mixture of about 300 compounds, is more efficient against viruses than his single compounds (12). Samples of propolis from different geographical areas have different chemical structure, but the difference in biological effects is insignificant (13). Thats why the healing value of propolis is important as mixture of all natural compounds which plants have built in it (native propolis) and not by isolating single compounds or mixtures of some compounds (extracts of propolis).

Years-long results of questionnaire for people who preventively used NATIVE PROPOLIS confirm the absence of viral illnesses (colds, flu) and faster recovery when they used it at an early stage of illness. It is interesting that with native propolis in few cases of the mononucleoses illness (Epstein-Barrov virus) symptoms of illness were mildly expressed. Clinical results showed slight enlargement of specific parameters and the recovery period was considerably shorter. NATIVE PROPOLIS is powerful but harmless natural preparation for health preservation and recovery in viral illnesses.

LITERATURE:
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13. J Ethnopharmacol. 1999 Mar;64(3):235-40