Clinical experiences of local therapy with propolis preparations have shown good results in treating cervical ectopia, erosion, inflammation and vaginal inflammation.
Carcinomas
It has been proved at the Faculty of Natural Sciences and Mathematics in Zagreb that Croatian propolis has anti-tumour and anti-metastasizing effects on mammary gland carcinoma.
Research results of Ruđer Bošković Institute have shown that NATIVE PROPOLIS stimulates processes that prevent the formation of carcinomas of reproductive organs. Furthermore, it stops the progression of carcinoma and kills tumour and deformed cells.Cytostatics combined with propolis are more efficient in preventing the progression of carcinoma and its metastasizing and the side effects of chemotherapy are substantially diminished (nausea, weakness, vomiting, and the reduction in the quantity of corpuscles).
Therefore, the usage of propolis is important for protection of persons at increased risks for hereditary reproductive organs diseases and, with a compulsory physician recommendation, it can be used to treat the above mentioned diseases.
KIDNEYS
Antioxidative substances in propolis not only protect the kidneys from acute damage caused by some cytostatics (cisplatin) during chemotherapy, but also prevent forming of carcinoma on the kidneys.
LIVER
Ruđer Bošković Institute has determined that NATIVE PROPOLIS prevents liver damage caused by free radicals and enhances its antioxidative defence.
Tests conducted on mice have shown that, generally, propolis protects the liver from chemical toxins and alcohol, which is attributed to its ability to capture free radicals. Its protective effect is stronger than the well known substance glycyrrhizin, used by official medicine.
Carcinomas
Stops the growth of some kinds of liver tumours and kills cancerogenic cells.
Liver protection is important to chronic patients who must take medications regularly, in cases of liver diseases and to persons prone to alcohol abuse.
NATIVE PROPOLIS prevents lesion and strengthens the defence of the heart muscle from oxidative stress and free radicals that are formed under the influence of cardio-toxic substances.
The protective activity is especially important in cases of heart diseases and persons at risk for hereditary heart diseases.
Blood
Propolis improves the absorption of minerals (iron, calcium, phosphorus, magnesium) from the digestive system into the blood circulatory system.
Anaemia
In combination with pollen (NATIVE PROPOLIS), it increases resorption of iron into the blood and raises the level of haemoglobin in cases of iron deficiency anaemia (ferropenic anaemia).Tests conducted in Ruđer Bošković Institute have shown that the presence of NATIVE PROPOLIS in blood substantially reduces the level of free radicals, increases the antioxidative defence and prevents oxidative stress. Thus, it protects blood corpuscles from free radical damage.
Lymphatic system
It has been determined in laboratory conditions on the model of human leukaemia cells (HL-60) that one of the propolis components kills the tumour cells.
Using the DNA chip method in Ruđer Bošković Institute it has been determined that NATIVE PROPOLIS markedly strengthens the gene the lack of which leads to appearance of lymphatic system carcinoma.
The protective activity of NATIVE PROPOLIS is significant for groups at high-risk for hereditary blood diseases.
Propolis stops the reproduction of bacteria in the oral cavity, heals necrotic stomatitis, aphthae and candidiasis, prevents the forming of dental plaque and dental caries, reduces the painful sensitiveness of teeth, increases tooth enamel hardness, strengthens dental pulp, reduces the acute and chronic inflammation of gums (paradontosis).
Tests on mice have shown that propolis prevents the forming of cataract and enhances the antioxidative defence of blood and lens.
The same antioxidative as well as anti-inflammatory mechanisms protect the cornea from the results of chemical and mechanical injuries.
The effect of propolis on brain cells had been unknown in professional literature. Tests conducted by the Ruđer Bošković Institute have shown that the NATIVE PROPOLIS could protect the brain from damage and atrophy of nerve cells, particularly in cases of nervous system diseases (Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, diabetic neuropathy, neuritis, brain atherosclerosis, epilepsy, depression, schizophrenia, ischaemic-reperfusion brain injury, aging, etc.), because it:
-prevents the brain oxidative stress,
-increases antioxidative defence of the brain tissue,
-neutralizes free radicals in the brain,
-markedly strengthens the gene with a weakened function apparently linked to the damage of nerve cells and an increased risk of Parkinson’s disease,
-repairs the free-radicals induced DNA damage,
-strengthens the gene that aids transmission of nerve impulses
-stimulates the DNA replication in the brain.
In cases of brain tumour (glioma) it stimulates the organism to produce the drug by itself (immunosuppression therapy).
It has been proved that, in cases of brain stroke, propolis in synergy with the bee pollen (NATIVE PROPOLIS) increases the blood supply of the brain and facilitates the more rapid recovery of disrupted and lost functions.
Researches conducted in the Institute of Maritime Medicine in Split have shown that Croatian propolis has a stronger antioxidative effect than vitamins C and E and some synthetic antioxidants.
It was proved in Ruđer Bošković Institute that native propolis significantly reduces the level of free radicals in blood, especially in brain. This points to a possibility of its beneficial effect in treatment of neurodegenerative diseases (Parkinson’s disease, Alzheimer’s disease).
