Propolis research

The influence of propolis on human body

Tests on mice have shown that propolis prevents the forming of cataract and enhances the antioxidative defence of blood and lens.

The same antioxidative as well as anti-inflammatory mechanisms protect the cornea from the results of chemical and mechanical injuries.

Oral cavity

Propolis stops the reproduction of bacteria in the oral cavity, heals necrotic stomatitis, aphthae and candidiasis, prevents the forming of dental plaque and dental caries, reduces the painful sensitiveness of teeth, increases tooth enamel hardness, strengthens dental pulp, reduces the acute and chronic inflammation of gums (paradontosis).

Respiratory system

Propolis therapy or therapy that combines propolis with medications has been considerably effective in healing inflammation of nasal cavity, throat, sinusitis, inflammation of the vocal cords, bronchitis and pulmonary tuberculosis.

A clinical study of patients suffering from mild to medium asthma has shown that propolis reduces the frequency of seizures at night and considerably improves the ventilatory lung functions.

Lung cancer
Tests on animals have proved that propolis prevents forming of bronchial and alveolar cell carcinoma. Propolis treatment or treatment that combines propolis with cytostatics prevents metastasizing to the lungs. Research at Ruđer Bošković Institute has proved that NATIVE PROPOLIS protects the lungs from damage caused by free radicals and oxidative stress and prevents forming of lung cancer because it markedly strengthens the gene the lack of which leads to appearance of tumour. Furthermore, the research showed that NATIVE PROPOLIS stops the growth and kills the tumour cells.

Therefore, it is important to protect the lungs with propolis when inhaling increased quantities of oxygen (hyperbaric oxygen therapy, diving, increased physical exertion – athletes), working in polluted atmosphere (smog, chemical solvents, smoking), when suffering from pulmonary diseases and when at risk for possible hereditary pulmonary diseases.


NATIVE PROPOLIS prevents lesion and strengthens the defence of the heart muscle from oxidative stress and free radicals that are formed under the influence of cardio-toxic substances. The protective activity is especially important in cases of heart diseases and persons at risk for hereditary heart diseases.

Propolis improves the absorption of minerals (iron, calcium, phosphorus, magnesium) from the digestive system into the blood circulatory system.

In combination with pollen (NATIVE PROPOLIS), it increases resorption of iron into the blood and raises the level of haemoglobin in cases of iron deficiency anaemia (ferropenic anaemia).Tests conducted in Ruđer Bošković Institute have shown that the presence of NATIVE PROPOLIS in blood substantially reduces the level of free radicals, increases the antioxidative defence and prevents oxidative stress. Thus, it protects blood corpuscles from free radical damage.

Lymphatic system
It has been determined in laboratory conditions on the model of human leukaemia cells (HL-60) that one of the propolis components kills the tumour cells. Using the DNA chip method in Ruđer Bošković Institute it has been determined that NATIVE PROPOLIS markedly strengthens the gene the lack of which leads to appearance of lymphatic system carcinoma.

The protective activity of NATIVE PROPOLIS is significant for groups at high-risk for hereditary blood diseases.


The effect of propolis on brain cells had been unknown in professional literature. Tests conducted by the Ruđer Bošković Institute have shown that the NATIVE PROPOLIS could protect the brain from damage and atrophy of nerve cells,

particularly in cases of nervous system diseases (Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, diabetic neuropathy, neuritis, brain atherosclerosis, epilepsy, depression, schizophrenia, ischaemic-reperfusion brain injury, aging, etc.), because it:

-prevents the brain oxidative stress,
-increases antioxidative defence of the brain tissue,
-neutralizes free radicals in the brain,
-markedly strengthens the gene with a weakened function  apparently linked to the damage of nerve cells and an increased  risk of Parkinson’s disease,
-repairs the free-radicals induced DNA damage,
-strengthens the gene that aids transmission of nerve impulses
-stimulates the DNA replication in the brain.

In cases of brain tumour (glioma) it stimulates the organism to produce the drug by itself (immunosuppression therapy).

It has been proved that, in cases of brain stroke, propolis in synergy with the bee pollen (NATIVE PROPOLIS) increases the blood supply of the brain and facilitates the more rapid recovery of disrupted and lost functions.

Digestive system

Propolis has a healing effect on the digestive system. It stimulates its regular functioning and protects stomach cells from alcohol-caused damage.
Experiences with NATIVE PROPOLIS show that it can be effective in constipation prevention.

Gastric ulcer and duodenal ulcer Due to its anaesthetic and healing properties, propolis has been used in treatment of gastric and duodenal ulcer for a long time. The practice of using NATIVE PROPOLIS has shown rapid healing effect on duodenal ulcers.This is probably due to its anti-inflammatory properties, forming of film over the mucous membrane, reduction of gastric acidity and soothing the smooth musculature cramps.

Large intestine inflammation
Clinical as well as our own experiences in the application of propolis have shown a very beneficial effect on chronic large intestine inflammation (colitis).

Large intestine carcinoma
It prevents lesion of the large intestine that can cause the development of carcinoma. When the carcinoma has already developed it slows down its growth, kills the tumour cells and reduces the risk of metastasizing to the liver. Combined with cytostatics, it diminishes the progress of abdomen carcinoma considerably and the recuperation of white and red blood cells is more rapid, compared to using only cytostatics.
Therefore, it could be used, with a compulsory physician recommendation, in addition to the cytostatic therapy, because it improves the immune system and alleviates the consequences of chemotherapy.

Kidneys and liver

Antioxidative substances in propolis not only protect the kidneys from acute damage caused by some cytostatics during chemotherapy, but also prevent forming of carcinoma on the kidneys.

Ruđer Bošković Institute has determined that NATIVE PROPOLIS prevents liver damage caused by free radicals and enhances its antioxidative defence. Tests conducted on mice have shown that, generally, propolis protects the liver from chemical toxins and alcohol, which is attributed to its ability to capture free radicals. Its protective effect is stronger than the well known substance glycyrrhizin, used by official medicine.

Stops the growth of some kinds of liver tumours and kills cancerogenic cells. Liver protection is important to chronic patients who must take medications regularly, in cases of liver diseases and to persons prone to alcohol abuse.

Reproductive organs

Clinical experiences of local therapy with propolis preparations have shown good results in treating cervical ectopia, erosion, inflammation and vaginal inflammation.

It has been proved at the Faculty of Natural Sciences and Mathematics in Zagreb that Croatian propolis has anti-tumour and anti-metastasizing effects on mammary gland carcinoma.

Research results of Ruđer Bošković Institute have shown that NATIVE PROPOLIS stimulates processes that prevent the formation of carcinomas of reproductive organs. Furthermore, it stops the progression of carcinoma and kills tumour and deformed cells.Cytostatics combined with propolis are more efficient in preventing the progression of carcinoma and its metastasizing and the side effects of chemotherapy are substantially diminished (nausea, weakness, vomiting, and the reduction in the quantity of corpuscles).

Therefore, the usage of propolis is important for protection of persons at increased risks for hereditary reproductive organs diseases and, with a compulsory physician recommendation, it can be used to treat the above mentioned diseases.




Learn more about the workings of propolis on the organ. Click on the image for visual display.

The influence of propolis on human body



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