Propolis has a stronger antibacterial effect on gram-positive bacteria (streptococcus, staphylococcus) than on gram-negative bacteria (Salmonella, Escherichia coli, Proteus spp., Pseudomonas aeruginosa).

Furthermore, it is beneficial in treatment of tuberculosis in human patients. It is interesting to note that, even when it is not directly effective against gram-negative bacteria, propolis creates protection against inflammation caused by those bacteria (Klebsiella pneumoniae, Proteus vulgaris, Pseudomonas aeruginosa).

The effect is less strong as well as less toxic than that of antibiotics, it does not cause bacteria resistance and it does not damage healthy intestinal flora.

When used in synergy with some of the antibiotics, the time of recovery is significantly reduced.

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